Recursive Adaptation

Recursive Adaptation

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By making suzetrigine cheap, we could cut opioid prescriptions in half
A win / win / win deal for the public, the government, and the drugmaker can cut the Gordian knot of pain prescription tradeoffs.
Feb 10 • Nicholas Reville
NYTimes Covers Our GLP-1s for Post-Incarceration Women Program
"I used to have these dreams where I was using opiates and then I’d wake up and want them. I don’t have those anymore."
Oct 14, 2025 • Nicholas Reville
My podcast episode with Chris Hayes
Chris interviewed me about addiction medicine, GLP-1s, and innovation policy.
Jan 14, 2025 • Nicholas Reville
NIH High Leverage Trials (HILT) Proposal
Large-scale Research for Repurposing and Supplements
Feb 3 • Nicholas Reville
Preventing online gambling addiction: briefing for state policymakers Feb 3rd
Effective policy interventions to reduce gambling addiction and bankruptcies.
Feb 2 • Nicholas Reville
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GLP-1 for Addiction: the Medical Evidence for Opioid, Nicotine, and Alcohol Use Disorder
May 14, 2024 • Nicholas Reville and Zarinah Agnew
Addiction Predictions for 2025 and Beyond
Dec 28, 2024 • Nicholas Reville
Wegovy and Ozempic (semaglutide) are associated with a 50-56% reduction in alcohol addiction
May 30, 2024 • Nicholas Reville
An Innovation Agenda for Addiction
Dec 10, 2024 • Nicholas Reville and Will
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Phase 3 trials of supplements and off-patent drugs can generate a windfall for the public
Better medicines, lower costs, and faster time to market.
Jan 29 • Nicholas Reville
Addiction by Design: "More people are implicated in this problem than we imagine"
A conversation with author and gambling expert Natasha Schull
Jan 26 • Noah Davis
The App stores should remove online gambling apps
These apps are far more dangerous than already blocked apps about alcohol, smoking, or sex.
Jan 21 • Nicholas Reville
Addiction predictions: How did I do for 2025?
I did... ok? decent? pretty good? messy?
Jan 20 • Nicholas Reville
DraftKings is the Purdue Pharma of gambling
51% of sports betting app revenue comes from 'problem gamblers', people who have become addicted.
Jan 9 • Nicholas Reville
CASPR GLP-1 event with Congressional Addiction Caucus on Jan 13
If you are in DC, we'd love to have you join us.
Jan 7 • Nicholas Reville
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