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100. Genetic Testing and the CYP450 Pathway, Part 1
Informing Psychiatric Medication Response
Apr 4, 2023
•
Brooke Siem
13
10
2
Most Popular
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152. Garbage In, Garbage Out: Every Failure of Sameer Jauhar, et.al's New Paper on Antidepressant Withdrawal
Jul 10, 2025
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Brooke Siem
30
6
6
162. A hypothesis on why hyperbolic tapering can still result in antidepressant withdrawal
Jan 7
•
Brooke Siem
24
6
6
154. Antidepressants Affect Every System in the Body — and Even Leading Withdrawal Researchers Are Missing It
Aug 11, 2025
•
Brooke Siem
26
12
4
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163. Why Making Meaning Matters in Antidepressant Withdrawal
A response to scientific dogma and "spiritual bypassing"
Feb 8
•
Brooke Siem
13
10
3
162. A hypothesis on why hyperbolic tapering can still result in antidepressant withdrawal
Using Chris Masterjohn, PhD's work to connect dots across SSRI withdrawal
Jan 7
•
Brooke Siem
24
6
6
161. Could the Sigma-1 Receptor Explain SSRI Withdrawal?
Exploring a neglected pathway with major implications for tapering
Dec 10, 2025
•
Brooke Siem
12
3
160. The Real World Harms of Post SSRI Sexual Dysfunction
A conversation with Angie Peacock
Nov 13, 2025
•
Brooke Siem
11
2
1
159. Psychiatric Drugs Interlude: The Real World is Where the Harms Live
A roundtable discussion between Brooke Siem, Dr. David Healy, Angie Peacock, David Antonuccio, PhD., and Kim Witzak
Oct 30, 2025
•
Brooke Siem
8
2
158. Why SSRIs Aren't Actually Interchangeable
We’ve spent decades chasing “low serotonin,” when we should have been asking which serotonin systems each drug disrupts.
Oct 14, 2025
•
Brooke Siem
16
5
157. SSRIs and the False Comfort of Selectivity
Rebranding SSRIs as Systemic Sabotage of Real Intelligence.
Oct 3, 2025
•
Brooke Siem
13
2
2
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May Cause Side Effects with Brooke Siem
Investigating the untold history of psychiatry, the science of antidepressant withdrawal, and stepping back into the soul after psychiatric drugs.
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