Zach Siegel

Zach Siegel

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News Digest: 2/20
RIP Frederick Wiseman, legend of the longest form, who I argue accidentally predicted Clavicular in the 1990s, died. I wrote about The Pitt for Wired. I…
22 hrs ago • Zachary Siegel
Friday News Digest: 2/13
Psychoanalyzing the Epstein Class, NYT cannabis editorial, flawed drug tests hurts new parents, the Anthropic media blitz and why I think "AI" (LLMs) do…
Feb 13 • Zachary Siegel
Friday News Brief: 1/30
Trump signs executive order: "The Great American Recovery Initiative."
Jan 30 • Zachary Siegel
ChatGPT is not your "harm reduction buddy"
ChatGPT admitted to me that it produced drug advice that "sounded knowledgeable but was medically reckless." The LLM conflated sycophantic design with…
Jan 29 • Zachary Siegel
Friday's (frozen) news digest: 1/22
Judge tosses "fentanyl exposure" case, Matt Bruenig on AI, Snap Inc. settles social media addiction lawsuit, what's up injectable buprenorphine, and…
Jan 23 • Zachary Siegel
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Kamala Harris Went After Big Pharma: Vivitrol and Suboxone
Aug 1, 2024 • Zachary Siegel
A Monster Courting Disaster
Dec 31, 2025 • Zachary Siegel
Sam Quinones is Wrong, Again
Feb 9, 2024 • Zachary Siegel
"Fentanyl Exposure" in 8 Charts
May 31, 2024 • Zachary Siegel
Friday News Brief: 1/16
What went down this week: White House reverses SAMHSA cuts, fentanyl supply shock, overdose deaths continue decline, doing molly with Kyrsten Sinema...
Jan 16 • Zachary Siegel
The "drug war" does not mean anything
Drugs and "narco-terrorism" are used to create a shape-shifting enemy.
Jan 9 • Zachary Siegel
Unemployed: Day 1
It's Monday Jan 5. 2026, the first day in over a decade that I do not have a job. Plus, my thoughts on a new anti-fentanyl vaccine funded by the DoD…
Jan 5 • Zachary Siegel
A Monster Courting Disaster
Welcome back newsletter. Update on my beat. What I learned covering the harm reduction movement. Where I go next.
Dec 31, 2025 • Zachary Siegel
We Live In A Lonely World
Our politics misses something crucial about how it feels to be alive today.
Nov 7, 2024 • Zachary Siegel
Ryan Hampton's New Book: "Fentanyl Nation"
There's a new book coming out that I wanna talk about.
Aug 19, 2024 • Zachary Siegel
Kamala Harris Went After Big Pharma: Vivitrol and Suboxone
Kamala Harris took on drug companies that made medicine to treat opioid use disorder.
Aug 1, 2024 • Zachary Siegel
Zach Siegel
Zach Siegel
Zach Siegel's Substack, written by Zach Siegel
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